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The Nike Odyssey React Men's Running Shoe provides crazy comfort that lasts as long as you can run. Its Nike React foam cushioning is responsive yet lightweight, durable yet soft. This attraction of opposites creates a sensation that not only enhances the feeling of moving forward, but makes running feel fun, too. The Nike Odyssey React's upper is built with a lightweight, breathable fabric instead of the premium Flyknit featured on the Nike Epic React.